Polyvinylpyrrolidone (PVP)

Polyvinylpyrrolidone (PVP) of average molecular weight (360,000) has been used for the intracytoplasmic sperm injection (ICSI) procedure to decrease the motility of spermatozoa, prevent their sticking to the injection pipette during the procedure, and to give more control over the flow of fluid in the ICSI needle (Palermo G et al., Fertil Steril., 1993;59(4):826-835). Seven and ten percent viscosities allows for better sperm function as well as improved visibility to detect sperm.

SAGE Micromanipulation Media are designed to facilitate the in vitro preparation of gametes prior to micromanipulation procedures, such as intracytoplasmic sperm injection (ICSI), assisted hatching, and embryo micromanipulation/blastomere removal. All of our micromanipulation media are one-cell fresh mouse embryo quality controlled, resulting in consistent product quality and reliability that enhances your success rates.